Pendleton, New York is an unincorporated hamlet in the town of Pendleton in Niagara County, New York, USA. Pendleton is a town on the southern edge of Niagara County, New York, United States. It is east of the city of Niagara Falls and southwest of the city of Lockport. The population was 6,397 at the 2010 census.The town of Pendleton was set apart in 1827 from part of the town of Niagara. Sylvester Pendleton Clark, one of the first settlers, gave his name to several locations in the town and eventually to the town itself. Clark served in the American Revolution and became an innkeeper and postmaster.