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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Quadratic unconstrained binary optimization (QUBO) is a pattern matching technique, common in machine learning applications. QUBO is an NP hard problem. QUBO problems are particularly well suited for processing on quantum computers. A quantum computer is a device for computation that makes direct use of quantum mechanical phenomena, such as superposition and entanglement, to perform operations on data. Quantum computers are different from traditional computers based on transistors. The basic principle behind quantum computation is that quantum properties can be used to represent data and perform operations on these data.