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High Quality Content by WIKIPEDIA articles! X-linked severe combined immunodeficiency (X-SCID) is an immunodeficiency disorder that affects lymphocytes. It is a recessive trait stemming from a defective version of the gene responsible for the functionality of the Interleukin 2 receptor (IL2RG). Persons afflicted with X-SCID often have infections very early in life, before three months of age. This is followed by pneumonitis, an inflammation of the lung which produces common symptoms such as cough, fever, chills, and shortness of breath. In addition, moniliasis, a type of fungal infection, is a telltale sign of X-SCID. Moniliasis involves moist areas of the body such as skin, the mouth, respiratory tract, and vagina. Symptoms of moniliasis include difficulty in swallowing, pain on swallowing and oral lesions.